Events List

DateEvent TypeSpeaker
10/01/2024Special SeminarDavid Hogg et. al [ + ]
10/01/2024No Astro Seminar [ + ]
10/02/2024ArXiv Discussion [ + ]
10/02/2024HEP SeminarHerman Verlinde [ + ]
10/03/2024Astro Research GroupHogg/Blanton [ + ]
10/03/2024Pullen Group Meeting [ + ]
10/03/2024Physics Dept ColloquiumSubir Sachdev [ + ]
10/04/2024Informal Astro TalkClaire Lamman [ + ]
10/04/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
10/07/2024CCPP Brown BagGlennys Farrar [ + ]
10/07/2024Astro Journal Club [ + ]
10/08/2024Special SeminarDavid Hogg et. al [ + ]
10/08/2024Astro SeminarFabio Pacucci [ + ]
10/09/2024ArXiv Discussion [ + ]
10/09/2024HEP SeminarAditya Parikh [ + ]
10/10/2024Astro Research GroupHogg/Blanton [ + ]
10/10/2024Physics Dept ColloquiumKurt Kremer [ + ]
10/11/2024Informal HEP TalkAzadeh Maleknejad [ + ]
10/11/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
10/14/2024Holiday [ + ]
10/15/2024Special SeminarDavid Hogg et. al [ + ]
10/15/2024Astro SeminarAlisa Galishnikova [ + ]
10/16/2024ArXiv Discussion [ + ]
10/16/2024HEP SeminarShirley Li [ + ]
10/17/2024Astro Research GroupHogg/Blanton [ + ]
10/17/2024Pullen Group Meeting [ + ]
10/17/2024Physics Dept ColloquiumKenneth Burch [ + ]
10/18/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
10/21/2024CCPP Brown BagWenzer Qin [ + ]
10/21/2024Astro Journal Club [ + ]
10/22/2024Informal Astro TalkTom Wagg [ + ]
10/23/2024ArXiv Discussion [ + ]
10/23/2024HEP SeminarAkaxia Cruz [ + ]
10/24/2024Astro Research GroupHogg/Blanton [ + ]
10/24/2024Pullen Group Meeting [ + ]
10/25/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
10/28/2024CCPP Brown BagDavid Dunsky [ + ]
10/28/2024Astro Journal Club [ + ]
10/29/2024Special SeminarDavid Hogg et. al [ + ]
10/30/2024ArXiv Discussion [ + ]
10/30/2024HEP SeminarZohar Komargodski [ + ]
10/30/2024Physics Dept ColloquiumJuan de Pablo [ + ]
10/31/2024Astro Research GroupHogg/Blanton [ + ]
10/31/2024Pullen Group Meeting [ + ]
11/01/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
11/04/2024CCPP Brown BagThavisha Dharmawardena [ + ]
11/04/2024Astro Journal Club [ + ]
11/05/2024Special SeminarDavid Hogg et. al [ + ]
11/05/2024Astro SeminarNikole Lewis [ + ]
11/06/2024ArXiv Discussion [ + ]
11/07/2024Astro Research GroupHogg/Blanton [ + ]
11/07/2024Pullen Group Meeting [ + ]
11/08/2024Informal HEP TalkJan Kożuszek [ + ]
11/08/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
11/11/2024CCPP Brown BagChirag Modi [ + ]
11/11/2024Astro Journal Club [ + ]
11/12/2024Astro SeminarTBA [ + ]
11/13/2024ArXiv Discussion [ + ]
11/13/2024HEP SeminarIbrahima Bah [ + ]
11/14/2024Astro Research GroupHogg/Blanton [ + ]
11/14/2024Pullen Group Meeting [ + ]
11/15/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
11/18/2024CCPP Brown BagMonica Pate [ + ]
11/18/2024Astro Journal Club [ + ]
11/19/2024Special SeminarDavid Hogg et. al [ + ]
11/19/2024Astro SeminarAndrew Saydjari [ + ]
11/20/2024ArXiv Discussion [ + ]
11/20/2024HEP SeminarLeah Jenks [ + ]
11/21/2024Astro Research GroupHogg/Blanton [ + ]
11/21/2024Pullen Group Meeting [ + ]
11/22/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
11/25/2024CCPP Brown BagChris Dessert [ + ]
11/25/2024Astro Journal Club [ + ]
11/26/2024Special SeminarDavid Hogg et. al [ + ]
11/26/2024Astro SeminarNadia Zakamska [ + ]
11/27/2024ArXiv Discussion [ + ]
11/28/2024Holiday [ + ]
11/28/2024Astro Research GroupHogg/Blanton [ + ]
11/28/2024Pullen Group Meeting [ + ]
11/29/2024Holiday [ + ]
11/29/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
12/02/2024CCPP Brown BagJeremy Tinker [ + ]
12/02/2024Astro Journal Club [ + ]
12/03/2024Special SeminarDavid Hogg et. al [ + ]
12/03/2024Astro SeminarRavi Sheth [ + ]
12/04/2024ArXiv Discussion [ + ]
12/05/2024Astro Research GroupHogg/Blanton [ + ]
12/05/2024Pullen Group Meeting [ + ]
12/05/2024Physics Dept ColloquiumWilliam Gelbart [ -- ]

Title: Self-Assembly, Gene Delivery, and Immunotherpay
Abstract: Apologies for the grandiose title, but I’m presenting an approach to gene delivery and immunotherapy that is based on the physics of self-assembly of virus-like particles. By gene delivery I mean the in vivo delivery of genes in messengerRNA (mRNA) form, to targeted cells; and by immunotherapy I mean the in vivo transformation of immune cells – either antigen-presenting cells for vaccination, or killer-T cells for clearing virus-infected or cancerous cells. The virus-like particles are each nothing more than a single mRNA molecule packaged inside an icosahedrally-symmetric protein shell, with or without a lipid bilayer envelope containing a second shell of icosahedrally-ordered proteins. These particles are either synthesized in vitro from purified RNA and protein components, or in cellulo; they are functionalized with antibodies targeting them to specific cells; and they are thermodynamically stable and resistant to nuclease digestion of their mRNA content. Because they contain therapeutic mRNA rather than a viral genome, they are not infectious. But in essentially every other way they resemble – in structure and in gene-delivery function – the highly-evolved virus particles on which their design is modeled. Indeed, our aim is to learn from a billion years of evolution about how viruses have perfected the art of protecting their genes and targeting them to the right cells. (4:00 PM - 5:30 PM, 726 Broadway, 940, CCPP Seminar)
12/06/2024Big Apple ColloquiumAndrea Ghez [ + ]
12/06/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
12/09/2024CCPP Brown BagAnna Suliga [ + ]
12/09/2024Astro Journal Club [ + ]
12/10/2024Special SeminarDavid Hogg et. al [ + ]
12/10/2024Astro SeminarKeith Hawkins [ + ]
12/11/2024ArXiv Discussion [ + ]
12/12/2024Astro Research GroupHogg/Blanton [ + ]
12/12/2024Pullen Group Meeting [ + ]
12/13/2024Holiday Party [ + ]
12/13/2024HEP Discussion SessionsQ. Weller and M. Calkins [ + ]
12/19/2024Pullen Group Meeting [ + ]
12/24/2024Holiday [ + ]
12/25/2024Holiday [ + ]
12/26/2024Holiday [ + ]
12/27/2024Holiday [ + ]
12/30/2024Holiday [ + ]
12/31/2024Holiday [ + ]
01/01/2025Holiday [ + ]
01/24/2025CUWiP [ + ]
02/10/2025CCPP Brown BagEmily Davis + Ken Van Tilburg [ + ]
03/05/2025HEP SeminarGiorgio Gratta [ + ]
03/12/2025HEP SeminarJunwu Huang [ + ]
03/19/2025HEP SeminarDaniel Harlow [ + ]
03/24/2025Holiday [ + ]
03/25/2025Holiday [ + ]
03/26/2025Holiday [ + ]
03/27/2025Holiday [ + ]
03/28/2025Holiday [ + ]